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Breast Cancer

Breast cancer is the one of the commonest malignancies afflicting women. In some parts it is the most common malignancy. It is currently estimated that one in 14 of all female children born will develop breast cancer in their lifetime.

Despite extensive investigation into the cause of breast cancer there is still no known cause.

What are the risk factors for breast cancer?
The exact cause of breast cancer is not known and most likely involves many factors:
Geographical: It is much more common in the western world.
Genetic: A family history of breast cancer will increase the risk of developing breast cancer in a woman by three to five times. Recently, a breast cancer gene (BR CA 1) has been identified. If a woman has this gene present in her chromosomes, there is an 85% chance of developing either breast or ovarian cancer, or both in her lifetime.
HorJennal: It appears to be more common in women who did not bear children. It is also less common in women who have their first child at early age.

Women who started their menstrual periods before age 12, those who delayed menopause until after age 55, and those who had their first pregnancy after age 30 have a mildly increased risk of developing breast cancer (less than two times the normal risk).

What factors have a protective effect?
Pregnancy and breast feeding have a protective effect in preventing breast cancer.

How is breast cancer diagnosed?

Screening:
The prognosis of breast cancer is closely related to the stage of disease at the time of diagnosis, therefore screening for breast cancer is extremely important. Numerous studies have confirmed that populations which get screened for breast cancer yield patients having much smaller tumors with much better prognosis. Currently, mammography and breast examination serve as the foundation in screening for breast cancer. Mammography is an x-ray examination of the breast. It has the ability to detect a cancer in the breast when it is quite small, long before it may be felt by breast examination. Eighty-five to 90% of all breast cancers are detectable by mammography. Approximately 10 to 15 percent of breast cancers are not visible on mammography, but can be felt on physical examination of the breast.

The importance of Breast Self Examination cannot be overstressed. A percentage of breast cancers is not seen on mammography and it is extremely important for a woman to perform Breast Self Examinations.

Currently, it is recommended that a woman should have a baseline mammogram between the ages of 35 and 40 years. Between 40 and 50 years of age mammograms are recommended every other year. After age 50 years, yearly mammograms are recommended.

Other diagnostic tests and procedures:
Ultrasound: An ultrasound is a test that uses sound waves to visualize structures inside the body. It is often used to distinguish between cysts and solid tumors in the breast. Fluid within cysts can be aspirated (withdrawn with a needle and syringe) for analysis in the laboratory.

Biopsy: It is a procedure which involves removal of a piece of tissue to analyze under the microscope. Biopsy still remains the only confirmatory test for breast cancer.If an area of the breast is suspicious for a cancer, a biopsy is usually performed to confirm or deny the diagnosis.

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